A semi-synthetic drug, Lysergic acid diethylamide (LSD), is hallucinogenic. It is also known by names like acid, dots, tabs and blotter. It is a potent and mood-changing chemical. Its effects typically are altered thoughts, moods, feelings, perceptions and awareness of one’s surroundings.
LSD is clear or white in colour, is odourless and slightly bitter in taste. It is sold on the streets in the form of tablets, gelatin squares, capsules or in liquid form.
How to make LSD
Albert Hoffmann first made LSD in 1938 from lysergic acid, which is a chemical derived from ergot fungus which grows on grains like rye and other related grains. To produce LSD, one needs to have strong knowledge of organic chemistry and would require a laboratory setup, the ability to sterilize equipment’s, a dark room and chemicals that are currently either restricted for sales or chemicals whose sales are closely monitored by the Drug Enforcement Agency (DEA).
LSD can be made in different ways. Let us have a look:
- LSD From Ergot
Ergot is highly toxic. The chemist needs to obtain ergot fungus and, with due care and preciseness, should culture it to extract ergot alkaloids. Then, it is synthesized into the lysergic acid compound by adding chemicals and heating processes. The compounds thereafter obtained are isomerized to produce active LSD. The LSD obtained is then purified and crystallized.
- LSD From Morning Glory
LSD can also be made from morning glory seeds and seeds of some related plants. Morning Glory seeds contain LSA or lysergic acid amide, which is hallucinogenic and produces a mild high. It is a precursor to LSD, but the chemical conversion of LSA into LSD is a cumbersome process; moreover, morning glory seed sold in the market are treated with toxic pesticide coating. To produce LSD using Morning Glory seeds requires lab equipment and hazardous and restricted chemicals.
The darkroom setup here becomes necessary because the fungus will decay under bright light.LSD production needs a strong working ability of organic chemistry, a full laboratory setup(also considering the ability to sterilize equipment as well as access to a darkroom), and some chemicals that are recently either sale restrained.
Contrary to the chemicals used for the production of methamphetamine, they can not be found in common household items. Note that there are many ways to make LSD. Some methods may begin with lysergic acid. Other methods may make use of morning glory seeds, which are known to be dangerous because of their toxic coating. Morning glory seeds and some others consist of LSA which could be removed from the seeds to make a mild high on its own.
Even though the amount of LSA in different seeds differs so much that the quality of the drug made from it would also vary. We will start with ergot which is a very poisonous substance an LSD chemist Should be careful when working with ergot as stated above to be very poisonous. Immediately the chemist gets the fungus, he or she must be very cautious and culture it to remove the ergot alkaloids. Here the darkroom setup now becomes very relevant because the fungus will decay under bright light, and LSD itself may break down faster when exposed.
Furthermore, the ergot alkaloids are fused into a lysergic acid compound named iso-lysergic acid hydrazide, through the addition of chemicals and heating processes. Iso-lysergic acid hydrazide is changed, which means that the atoms in its molecules are organized through a chemical process. It is first cooled, fused with an acid and a base and evaporated. what is left Iso-lysergic diethylamide, which is isomerized again to manufacture active LSD. The LSD is then purified and crystallized.
Why is LSD Tolerance Important?
Tolerance is defined as the body’s natural resistance or decreased responsiveness to a drug’s effect. LSD’s effectiveness reduces if it is used rapidly over a short span of time. LSD tolerance refers to both physiological and psychological effects of the drug. The more frequently LSD is consumed, the less intense will be the hallucinations. The body’s tolerance to LSD is important as it reduces mood-altering, hallucinations and perceptual distortions.
Medical: LSD as of now has no certified use in medicine there was a meta-analysis that concluded a dose was useful at reducing alcohol intake in alcoholism. LDS had also been studied in depression anxiety and medicine dependence with positive prior results
Secondly, Spiritual LSD can effectuate intense spiritual experience and is therefore considered a hallucinating substance, some users of persons who have taken it have given reported out of body experiences. Mystical experience seen during LSD sessions appears to be intentionally indistinguishable from alike descriptions in the sacred scriptures of some religions.
Thirdly, LSD is commonly used as a recreational medicine in the company of friends, a multitude or by oneself.
LSD 25 vs LSD
LSD 25 is a derivative of LSD. LSD was first synthesized as part of the research program to find ergot alkaloid derivatives’ medical usefulness. LSD was synthesized as a potential medical therapy for respiratory depression and other ailments. LSD 25 was created by reacting lysergic acid with diethylamine, an organic derivative of ammonia.
LSD is not addictive. its consistent use can make acute tolerance requiring much bigger doses to feel an effect. Adverse psychiatric reactions are liable such as anxiety, paranoia and delusions. stressful flashbacks may come to the occurrence. Death as a result of LSD is not known in rare cases but death may also occur as a result of extreme negative behaviours. It breaks down when exposed to ultraviolet rays. moreso, it could increase blood pressure and body temperature.
While the acute and the chronic psychotomimetic qualities of the hallucinogen (LSD-25) acknowledge for almost 40years. That additional types of biological outcome should have come under scrutiny was directly applicable to widespread use.
To conclude this two have very similar characteristics.
Why is LSD Addictive
LSD does not cause a physical addiction but can trigger behavioural addiction. In simple words, it does not trigger drug-seeking behaviour, but people can become addicted to visual hallucinations and illusions they experience while “tripping”. People may become psychologically dependent on it because they enjoy the feelings they experience and the impact it makes on their behaviour, emotions and thoughts, which is what causes LSD’s abuse.
Firstly, an acid trip can last up to 12hours, or even longer in other cases. Even a minuscule dose of LSD can result in a long trip or episode, and there are such realistic seeming ideological changes that happen in the mind of the user that they may injure themselves or others during one of these experience.
As a matter of fact, a psychological addiction may occur if a physician does not they feel like they need to take the drug to be creative or feel like themselves even though LSD does not manufacture effects that are wanting all the time like euphoria and can cause adverse reactions that may result to fear, anxiety and paranoia. Consistent use of this drug can lead to negative effects on the person’s thoughts, emotions and behaviour.
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